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Newsletter
New Products
 
New ELFN1 antibody with excellent results in WB and ICC applications

ELFN1, extracellular leucine-rich repeat and fibronectin-III domain containig protein 1 also called Ppp1r28, is a post-synaptic cell adhesion protein that regulates circuit dynamics in the CNS by modulating the temporal dynamics of interneuron recruitment. Specifically enriched in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons. ELFN1 is also thought to play a role in cone photoreceptor wiring.       
 
Indirect immunostaing of PFA fixed rat hippocampus neurons with rabbit anti-ELFN1 (cat.no.: 448 003, dilution 1:500; red) and mouse anti-Synapsin 1 (cat. no.: 106 011, dilution 1:1000; green). Nuclei have been visualized by DAPI staining (blue).
 
New single domain antibody against S1 spike protein of Sars-CoV-2

The FluoTag-Q anti-S1 SARS-CoV-2 is based on the W25 clone, which has a sub-nanomolar affinity for the SARS-CoV-2 S1 protein receptor binding domain (RBD) and can neutralize infections as it efficiently competes with ACE-2 receptor binding.
 
PFA fixed SARS-CoV-2 infected cells stained with FluoTag-Q anti-S1 SARS-CoV-2 SC3 (cat. no.: N3501-SC3-L; red) and mouse anti-nucleocapsid (green). Nuclei were visualized by DAPI staining (blue).

Courtesy of Dr. Marco van Ham- HZI, Braunschweig
 
We have added several new interesting antibodies to our portfolio:
 
  • anti-ALDh1L1, ALDh1L1 is in the CNS a marker protein for astrocytes, show superior performance in ICC, IHC and IHC-P (FFPE) applications.
  • anti-VGLUT2 biotinylated mouse monoclonal antibody
  • anti-ChT polyclonal Guinea pig antibody, ideal for IHC-P (FFPE)
  • anti-S100A1 mouse monoclonal antibody
  • anti-Alfa tag rabbit polyclonal antibody
  • anti-Alfa tag affinity purified rabbit polyclonal antibody
  • anti-Alfa tag recombinant mouse monoclonal antibody
 
Our family of recombinant rabbit monoclonal antibodies has several new members:
 
  • anti-Calretinin rabbit monoclonal from clone 37C9
  • anti-GAD2/GAD65 rabbit monoclonal from clone 26H1D1
  • anti-GABA-A receptor alpha1 rabbit monoclonal from clone 53D1
  • anti-CD8a rabbit monoclonal from clone 321E9 (HistoSure product)
  • anti-CD3e rabbit monoclonal from clone 19G5B7 (HistoSure product)
 
Fluorescent tags are very important tools in biological research. We have broadened our spectrum of recombinant alpaca-derived single domain antibodies (sdAbs) that recognize the most recently introduced fluorescent proteins:
 
  • sdAb anti-mEOS recognizing a photo-switchable fluorescent protein
  • sdAb anti-mNeonGreen recognizing a very bright fluorescent protein
  • sdAb anti-mRuby recognizing a pH resistant fluorescent protein
 
For a complete list of new products, please visit the News section.
 

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Synaptic Systems Gesellschaft für neurobiologische Forschung, Entwicklung und Produktion mbH
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